Meltos (active agent – clenbuterol) is not an anabolic steroid, but rather a stimulant that belongs to a classification of compounds known as sympathomimetics. Clenbuterol’s original use as a medicine in the prescription drug market was (and still currently is) as a bronchodilator in the treatment of asthma. Upon activation of beta-2 receptors in the cell lining of the bronchial tubes, it initiates bronchial dilation (the opening and expanding of the airways) in the lungs, nose, and throat.
In bodybuilding clenbuterol is most commonly utilized in cutting, pre-contest, and fat loss cycles. Clenbuterol can bind to receptors on fat cells and initiate lipolysis. This effect involves its interaction with beta-2 adreno-receptors in fat tissue.
One important point to note is that through continued consistent use, clenbuterol will downregulate beta-2 receptors in the body in response to its stimulation of those receptors, and it occurs very quickly. The manifestation of this effect is diminished fat loss during use until the fat loss reaches a complete stop. There are two methods of remedying this effect. The first is to introduce time off from use of the drug for at least 2 weeks. The second is through the use of Ketotifen, an anti-histamine drug that is known for upregulating beta-2 receptors.
Clenbuterol is not an anabolic steroid, it does not express or exhibit any of the known side effects that are associated with anabolic steroid use. Instead, clenbuterol expresses side effects that are common to all drugs and compounds in the stimulant class. Perhaps the most unique of clenbuterol side effects is the commonly reported side effect of muscle cramping. The cause of this is through Clenbuterol’s depletion of taurine in the body. Taurine, alongside magnesium, potassium, and sodium, play very crucial roles in the regulation of bioelectrical nerve impulses and signals that govern the contraction and relaxation of all muscle tissue types. When taurine is depleted, involuntary and often intense and painful muscle contractions that lead to cramps can result. Supplementation with taurine at 2.5 – 5 grams per day can mitigate this side effect.
Clenbuterol may adversely affect the cardiovascular system and raises heart rate and blood pressure. Please take this into account prior to using it.
Other common clenbuterol side effects include tremors, insomnia, sweating, and nausea.
In order to achieve any significant amount of fat loss, the maximum сlenbuterol dosage should be no more than 120 – 160 mcg per day (for males).
WARNING: The dosage must be slowly ramped up to the maximum dosages mentioned. The initial starting dosage should not exceed 20-40 mcg for the first 2-4 days, after this the clenbuterol dosage is increased by another 20 mcg and so on. Titration downwards is not necessary when ending clenbuterol use.
Clenbuterol exhibits a half-life of approximately 37 hours, so all Clenbuterol dosages should ideally be consumed at once in the morning. There is no requirement to spread the clenbuterol dosages throughout the day, and this would in fact cause worse insomnia and sleep disturbances.
Here is some information I found to be helpful.
Clenbuterol has become a very common drug in the bodybuilding community, thanks to its ability to induce fat loss while preserving muscle mass. A 2014 study performed on clenbuterol toxicity concluded that bodybuilding is the most-cited use of the drug among those hospitalized with severe clen side effects (13). But despite the risks and side effects associated with this drug, it still remains popular among bodybuilders.
Considering the lack of legitimate clenbuterol studies performed on humans, the bodybuilding world remains one of the best (though not always credible) sources for information on the subject. Forums, such as the one here at EliteFitness.com, are often referred to for those seeking info on how to effectively use this drug for fat loss.
In many cases, bodybuilders cycle other drugs like Cytomel (T3) with clenbuterol to enhance fat-burning effects. These are commonly called "cutting" cycles, and they are sometimes run before a competition to promote a lean, vascular onstage look. Bodybuilders also add clenbuterol into anabolic steroid cycles to keep their weight down while trying to increase muscle mass/strength. This is another area where little scientific research has been done on humans. However, a 2010 study performed on paraplegic mice revealed that clenbuterol and testosterone propionate used together are more effective at reducing muscle atrophy than testosterone alone (14).
Knowledgeable bodybuilders also use ancillaries during a clenbuterol cycle to minimize the previously discussed side effects. Magnesium, potassium and/or taurine are often used for on-cycle support to prevent painful muscle cramps. It's also suggested that clen users drink more water than usual to counteract the excessive sweating that can occur on a clen cycle.
Most suggestions on how to use clenbuterol for weight loss come through anecdotal evidence from bodybuilders who've used the drug. So, referencing threads from the EliteFitness forums, let's examine some different aspects of human clenbuterol use, including dosage, a sample cycle, post-cycle therapy, expected results and common forms of this drug.
Dosing is largely dependent on a user's clenbuterol experience, sex and how well their body tolerates the drug. An oft-recommended starting clen dosage for male beginners is 20mcg per day. And, as discussed in this forum thread, men can increase their daily dosage to 60-80mcg if the side effects aren't too unbearable. Experienced users will dose anywhere from 100-140mcg per day. As for female users, 10mcg is a commonly recommended starting dose, while many women will go up to 40-60mcg daily with experience.
Clenbuterol Half Life
Clenbuterol's half life, or the amount of time it takes for the drug's effectiveness to fall to half of its beginning value, is around 26 hours. Clenbuterol is detectable in the blood for 48 hours after being taken (15). Both of these points are highly important to bodybuilders because they base dosage frequency on much of a drug is still active in their system. The key is to keep a steady stream of clen running in the body to experience enhanced fat-burning effects.
When running a clenbuterol cycle, a typical recommendation is to take this drug for two weeks, followed by a two-week break. The reason why is, due to clenbuterol saturating beta-2 receptors, the drug loses its fat-burning benefits over time. Taking a break allows these receptors to clear out and move closer to their "clean" pre-drug state. So a standard clen cycle sees bodybuilders use a 2-week-on, 2-week-off format for 6-10 weeks. Below you can see a sample clenbuterol cycle in this format, where the user tapers at the end to reduce their body's post-cycle shock:
40-120mcg (w/ taper down to 40mcg)
40-120mcg (w/ taper down to 40mcg)
Plus it come with a little something like it happened before.. the fat burn with my training program is unavailable. Thanks a lot pharmacom .
Good product ! Don't hesitate to order it !
In my opinion i like this way better than clen..no shakeyness
Breathing has improved dramatically in the morning and in the gym